We’re redefining how critical medicines are delivered
About
Pain-free
/
Fast
/
Needle-free
/
Reliable
/
Pain-free / Fast / Needle-free / Reliable /
We’ve developed a patented buccal drug delivery platform that enables rapid, reliable, pain-free systemic delivery of critical medicines, without injections, nasal sprays, or pills.
Many medicines fail to reach patients fast enough due to the limitations of existing delivery methods.
Injections are painful, require training, and create barriers to access
Nasal sprays can be unreliable due to congestion, positioning, and variable absorption
Oral pills are often too slow or unpredictable when rapid therapeutic effect is needed
In critical moments, these constraints limit access to reliable treatment.
Why medicine delivery matters
Onset of activity in under 5 minutes
Pain‑free and needle‑free
Works regardless of patient position or consciousness
Minimal training required
Suitable for pediatric, adult, and geriatric use
The Buckle Approach
Our patented buccal swab system delivers precision doses of medicine directly across the buccal mucosa and into systemic circulation, bypassing the gut and liver to achieve rapid onset comparable to traditional methods.
What sets us apart
Platform
Robust platform for needle-free, pain-free drug delivery in multi-billion dollar applications.
We’ve designed a proprietary combination of single‑use applicator with a bio‑adhesive formulation that overcomes traditional limitations of buccal delivery. The platform is designed to be scalable, cost‑effective, and adaptable.
Pipeline & programs
High-impact programs addressing urgent unmet needs.
The initial pipeline focuses on indications where speed, reliability, and ease of use are critical.
Naloxone
Opioid overdose reversal
Epinephrine
Allergic reactions and anaphylaxis
In the News
-
![]()
Buckle Therapeutics Reimagines Naloxone Delivery for Opioid Overdoses
September 4, 2025
Get in Touch
For partnership, investor, or general inquiries: submit a message or email us, BD@buckletx.com